Long histories of pathologisation have created narrow definitions of what it means to be autistic, thus limiting autistic people’s ability to articulate their own being. My research takes an interdisciplinary approach to interrogate the construction of autistic subjective and ontology within historical and contemporary clinical discourses of disability and neurology. I propose to use a unique theoretical framework informed by queer, trans, Black, decolonial, and disabled critiques to examine these narratives and to demonstrate the mechanisms of power through which autistic individuals are subjected and made ontological. My contribution to the literature rests on the assertion that, in contradiction to dominant discourses, autistic people construct new ways of being outside of normativity though art, performance, writing, and community building that resist subjectivising processes. My primary research question is: what is the epistemological significance of understanding autistic ontology through models of Black and trans subjectivities? I am interested in the new ontologies that might emerge from this research and how we may confer the power to determine subjectivity unto autistic people themselves.